Description Of Atypical Ductal Hyperplasia:
Atypical ductal hyperplasia (ADH) is not breast cancer, but is considered a precancerous condition. Atypical ductal hyperplasia indicates that there are more cells lining the duct than would normally be there, and some of these cells are not typical -- they are irregular in shape and size. Usually, a milk duct is lined with one even layer of uniformly shaped cells, but in ductal hyperplasia there may be many layers of cells. This is similar to atypical lobular hyperplasia.
Increased Risk For Breast Cancer:
Also Known As:
Signs And Symptoms:
Atypical ductal hyperplasia usually doesn't cause any notable symptoms. It is usually found when having a benign breast lump or thick area of tissue examined. In rare cases, atypical ductal hyperplasia may cause breast pain. Hyperplasia will show up on a mammogram or ultrasound, and then a tissue sample can be taken to get a clear diagnosis.
Tests Used to Diagnose ADH:
- Mammogram - appears as a pattern of calcifications on a mammogram
- Ultrasound - uses sound waves to reveal groups of calcifications
- Ductal Lavage - atypical ductal cells may be flushed out and examined under a microscope
- Breast Biopsy - a core needle biopsy, or open surgical biopsy will be used to take a tissue sample for testing in the pathology lab
Follow-Up After Diagnosis:
Treatments for Atypical Ductal Hyperplasia:
Many doctors advise their patients to take a "wait and see" approach to atypical ductal hyperplasia. Most cases will never develop into breast cancer. But if you are worried or are at high risk for breast cancer, then you can have that tissue removed.
- Ultrasound-Guided, Vacuum-Assisted Excision - a relatively noninvasive method of removing the atypical area of tissue
- Lumpectomy - surgery to remove the tissue and a margin of surrounding tissue, to help prevent recurrence
What A Diagnosis of Atypical Ductal Hyperplasia Means:
Non-Cancerous Breast Conditions: Hyperplasia. American Cancer Society. Last Revised: 09/16/2010.
Scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia at ultrasound-guided core needle biopsy. Ko E, Han W, Lee JW, Cho J, et al. Breast Cancer Res Treat. 2008 Nov;112(1):189-95.
Ultrasound-Guided, Vacuum-Assisted, Percutaneous Excision of Breast Lesions: An Accurate Technique in the Diagnosis of Atypical Ductal Hyperplasia. Ian Grady, Heidi Gorsuch, Shelly Wilburn-Bailey. Journal of the American College of Surgeons, 1 July 2005, Volume 201, Issue 1, Pages 14-17.