Definition: mTOR -- which stands for mammalian target of rapamycin -- is a protein that regulates vital cell growth processes. mTOR is similar to a communications command center -– it receives external signals from growth factors, hormones, and proteins. It then gives the 'on' or 'off' signals for the cell to grow and divide, seek nutrition, or use its nutrition.
Pronunciation: EM-tore
Also Known As: mammalian target of rapamycin, mammalian TOR, molecular target of rapamycin
Common Misspellings: imtor, emtor, emptor
Examples:
If a cell's mTOR is not properly regulating cell growth, it can contribute to the uncontrolled multiplication of cells, resulting in cancer. When this happens, your doctor may prescribe an mTOR inhibitor. Afinitor (everolimus) and Sirolimus are two examples of mTOR inhibitors.
