Can Grapefruit Raise Your Risk of Breast Cancer?

There has been some conflicting information published over the years regarding grapefruit, specifically as it relates to the risk of breast cancer. Some studies have shown a reduced risk of breast cancer, while others have shown the opposite.

This article will review the information currently available about grapefruit and breast cancer risk.

Studies on Grapefruit and Breast Cancer Risk

A study published in 2007 looked specifically at the link between breast cancer development and grapefruit intake in a group of 50,000 postmenopausal people with vaginas, and found that there is potentially a correlation between grapefruit intake and breast cancer. In that study, there was a 30% increase risk of breast cancer in people with vaginas who at at least a fourth of a grapefruit per day.

In contrast, a different study done in 2008 did not find the same results, showing no difference in breast cancer rates in people with vaginas who ate grapefruit regularly.

How Grapefruit Affects the Body

Grapefruit and grapefruit juice contain certain enzymes that can affect how the liver processes some medications. This altered process can lead to higher or lower levels of medications in the body. Considering this action, some research has shown that grapefruit may similarly lead to elevated estrogen levels in the body.

Grapefruit May Raise Estrogen Levels

A 2013 study showed the effect grapefruit had on estrogen levels in a person's body when eaten regularly. It was found that postmenopausal people who ate more grapefruit had higher estrogen levels. Further studies are needed on those who are premenopausal, with naturally higher levels of estrogen.

Grapefruit can also have an effect on the way medications used to treat breast cancer are absorbed by the body. The enzyme pathway, which grapefruit affects, can cause the liver (which is responsible for metabolizing many medications) to cause too much or too little of the medication to work.

Nutritional Value of Grapefruit

When thinking of the possibility that grapefruit could have an effect on postmenopausal breast cancer risk, it's important to weigh this against the potential benefits of adding grapefruit to a healthy diet. Grapefruit is rich in vitamin C as well as phytonutrients.

In studies of people who ate or drank grapefruit products regularly, they had better cholesterol levels, an overall healthier diet, and healthier body weight.

Summary

There have been multiple studies that have shown the benefits of eating grapefruit or drinking grapefruit juice regularly. Although there are many people that can possibly benefit from this, there are people who should avoid grapefruit, as it can interfere with their medications or potentially increase their risk of getting breast cancer. If you ever wonder if you should or should not be eating grapefruit, talk to your healthcare team.